Catalog: YN1185
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
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Main Information
Target
RAB5B
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB, ELISA
MW
23kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000; ELISA 1:5000-20000
Formulation
Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
Specificity
RAB5B Polyclonal Antibody detects endogenous levels of protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
23kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human protein . at AA range: 90-170
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Specificity:
RAB5B Polyclonal Antibody detects endogenous levels of protein.
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Gene Name:
RAB5B
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Protein Name:
Ras-related protein Rab-5B
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Background:
enzyme regulation:Regulated by guanine nucleotide exchange factors (GEFs) which promote the exchange of bound GDP for free GTP.,function:Protein transport. Probably involved in vesicular traffic.,similarity:Belongs to the small GTPase superfamily. Rab family.,subcellular location:Enriched in stage I melanosomes.,subunit:Binds EEA1. Interacts with RIN2 and RIN3, which probably regulate its pathway, possibly by acting as GEFs.,
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Function:
enzyme regulation:Regulated by guanine nucleotide exchange factors (GEFs) which promote the exchange of bound GDP for free GTP.,Function:Protein transport. Probably involved in vesicular traffic.,similarity:Belongs to the small GTPase superfamily. Rab family.,subcellular location:Enriched in stage I melanosomes.,subunit:Binds EEA1. Interacts with RIN2 and RIN3, which probably regulate its pathway, possibly by acting as GEFs.,
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Cellular Localization:
Cell membrane ; Lipid-anchor ; Cytoplasmic side . Early endosome membrane ; Lipid-anchor . Melanosome . Enriched in stage I melanosomes. .
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Tissue Expression:
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Research Areas:
>>Ras signaling pathway ;
>>Endocytosis ;
>>Phagosome ;
>>Vasopressin-regulated water reabsorption ;
>>Salmonella infection ;
>>Amoebiasis ;
>>Tuberculosis
>>Endocytosis ;
>>Phagosome ;
>>Vasopressin-regulated water reabsorption ;
>>Salmonella infection ;
>>Amoebiasis ;
>>Tuberculosis
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Signaling Pathway
Reference Citation({{totalcount}})
Catalog: YN1185
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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