Synthesized peptide derived from part region of human protein

GNAO Polyclonal Antibody detects endogenous levels of protein.

GNAO1

Guanine nucleotide-binding protein G(o) subunit alpha

The protein encoded by this gene represents the alpha subunit of the Go heterotrimeric G-protein signal-transducing complex. Defects in this gene are a cause of early-onset epileptic encephalopathy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2015],

Function:Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(o) protein function is not clear.,similarity:Belongs to the G-alpha family. G(i/o/t/z) subfamily.,subunit:G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.,

Cell membrane . Membrane ; Lipid-anchor .

Brain,Endometrium,Myometrium,

>>Rap1 signaling pathway ;
>>Circadian entrainment ;
>>Retrograde endocannabinoid signaling ;
>>Glutamatergic synapse ;
>>Cholinergic synapse ;
>>Serotonergic synapse ;
>>GABAergic synapse ;
>>Dopaminergic synapse ;
>>Long-term depression ;
>>Estrogen signaling pathway ;
>>Melanogenesis ;
>>Oxytocin signaling pathway ;
>>Relaxin signaling pathway ;
>>Morphine addiction ;
>>Alcoholism ;
>>Chagas disease ;
>>Toxoplasmosis ;
>>Human cytomegalovirus infection ;
>>Human immunodeficiency virus 1 infection