Catalog: YM9054
Size
Price
Status
Qty.
200μL
$600.00
3 weeks
0
100μL
$340.00
3 weeks
0
40μL
$190.00
3 weeks
0
Add to cart
Collected
Collect
Main Information
Target
Rab 10
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IF, IP, ELISA
MW
23kD (Calculated)
23kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200;
Formulation
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Specificity
Endogenous
Purification
Protein A
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
MW(Calculated)
23kD
MW(Observed)
23kD
Modification
Unmodified
Clonality
Monoclonal
Clone Number
PT1212R
Isotype
IgG,Kappa
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Antigen&Target Information
Specificity:
Endogenous
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Gene Name:
RAB10
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Protein Name:
Ras-related protein Rab-10
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Other Name:
RAB10 ;
Ras-related protein Rab-10
Ras-related protein Rab-10
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Background:
RAB10 belongs to the RAS (see HRAS; MIM 190020) superfamily of small GTPases. RAB proteins localize to exocytic and endocytic compartments and regulate intracellular vesicle trafficking (Bao et al., 1998 [PubMed 9918381]).[supplied by OMIM, Mar 2009],
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Function:
Function:May be involved in vesicular trafficking and neurotransmitter release.,similarity:Belongs to the small GTPase superfamily. Rab family.,
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Cellular Localization:
Cytoplasmic vesicle membrane ; Lipid-anchor ; Cytoplasmic side . Golgi apparatus membrane . Golgi apparatus, trans-Golgi network membrane . Endosome membrane . Recycling endosome membrane . Cytoplasmic vesicle, phagosome membrane . Cytoplasm, cytoskeleton, cilium basal body . Endoplasmic reticulum membrane . Cytoplasm, perinuclear region . Associates with SLC2A4/GLUT4 storage vesicles (PubMed:22908308). Localizes to the base of the cilium when phosphorylated by LRRK2 on Thr-73 (PubMed:20576682, PubMed:30398148). Transiently associates with phagosomes (By similarity). Localizes to the endoplasmic reticulum at domains of new tubule growth (PubMed:23263280). .
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Tissue Expression:
Research Areas:
>>Endocytosis ;
>>AMPK signaling pathway
>>AMPK signaling pathway
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Signaling Pathway
Reference Citation({{totalcount}})
Catalog: YM9054
Size
Price
Status
Qty.
200μL
$600.00
3 weeks
0
100μL
$340.00
3 weeks
0
40μL
$190.00
3 weeks
0
Add to cart
Collected
Collect
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