Endogenous

IFITM3

Interferon-induced transmembrane protein 3

IFITM3 ;
Interferon-induced transmembrane protein 3 ;
Dispanin subfamily A member 2b ;
DSPA2b ;
Interferon-inducible protein 1-8U

The protein encoded by this gene is an interferon-induced membrane protein that helps confer immunity to influenza A H1N1 virus, West Nile virus, and dengue virus. Two transcript variants, only one of them protein-coding, have been found for this gene. Another variant encoding an N-terminally truncated isoform has been reported, but the full-length nature of this variant has not been determined. [provided by RefSeq, May 2012],

induction:By alpha and gamma interferons.,similarity:Belongs to the CD225 family.,

Membranous

>>MAPK signaling pathway ;
>>Ras signaling pathway ;
>>Rap1 signaling pathway ;
>>Calcium signaling pathway ;
>>PI3K-Akt signaling pathway ;
>>Adherens junction ;
>>Signaling pathways regulating pluripotency of stem cells ;
>>Thermogenesis ;
>>Regulation of actin cytoskeleton ;
>>Parathyroid hormone synthesis, secretion and action ;
>>Pathways in cancer ;
>>Proteoglycans in cancer ;
>>Prostate cancer ;
>>Melanoma ;
>>Breast cancer ;
>>Central carbon metabolism in cancer