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Ki-67 (ABT001) Mouse mAb

-YM4905

Catalog: YM4905
Size
Price
Status
Qty.
200μL
$600.00
3 weeks

0

100μL
$340.00
3 weeks

0

40μL
$190.00
3 weeks

0

Add to cart

Collected

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Main Information
Target

Ki-67

Host Species

Mouse

Reactivity

Human,

Applications

IHC, WB, IF, ELISA

MW

359kD (Calculated)

359kD (Observed)

Conjugate/Modification


Unmodified

Detailed Information
Recommended Dilution Ratio
IHC 1:200-1000; WB 1:500-2000; IF 1:100-500; ELISA 1:1000-5000
Formulation
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Specificity
The antibody can specifically recognize human Ki-67 protein.
Purification
Protein G
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
MW(Calculated)
359kD
MW(Observed)
359kD
Modification
Unmodified
Clonality
Monoclonal
Clone Number
ABT001
Isotype
IgG2b,Kappa
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human Ki-67 AA range: 1200-1400
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Specificity:
The antibody can specifically recognize human Ki-67 protein.
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Gene Name:
MKI67
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Protein Name:
Ki 67
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Other Name:
Antigen identified by monoclonal Ki 67 ;
Antigen identified by monoclonal Ki-67 ;
Antigen KI-67 ;
Antigen KI67 ;
Antigen Ki67 ;
KI67_HUMAN ;
KIA ;
Marker of prolifeRation Ki-67 ;
MIB 1 ;
MIB ;
MKI67 ;
PPP1R105 ;
ProlifeRation marker protein Ki-67 ;
ProlifeRation related Ki 67 antigen ;
Protein phosphatase 1 regulatory subunit 105 ;
RP11-380J17.2
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Database Link:
Organism Gene ID SwissProt
Human 4288; P46013;
Background:
Ki-67 is a proliferating cell related nuclear protein, which is closely related to mitosis. It can recognize cells in G1, S, G2 and M phases except G0 phase. It is mainly used to judge the cell proliferation index. Ki-67 proliferation index is closely related to the degree of differentiation, invasion, metastasis and prognosis of many tumors. Therefore, it is also one of the important reference indexes for the prognosis of some malignant tumors. It is widely used as a marker of various malignant tumors and in tumor research.
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Function:
developmental stage:Expression of this antigen occurs preferentially during late G1, S, G2 and M phases of the cell cycle, while in cells in G0 phase the antigen cannot be detected.,Function:Thought to be required for maintaining cell proliferation.,online information:Ki-67 entry,similarity:Contains 1 FHA domain.,subcellular location:Predominantly localized in the G1 phase in the perinucleolar region, in the later phases it is also detected throughout the nuclear interior, being predominantly localized in the nuclear matrix. In mitosis, it is present on all chromosomes.,subunit:Interacts with KIF15. Binds through the FHA domain to MKI67IP.,
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Cellular Localization:
Nuclear
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Tissue Expression:
Nuclear
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Catalog: YM4905
Size
Price
Status
Qty.
200μL
$600.00
3 weeks

0

100μL
$340.00
3 weeks

0

40μL
$190.00
3 weeks

0

Add to cart

Collected

Collect

Customized Service

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