R

CD3 (ABT295) Mouse mAb

-YM4628

Catalog: YM4628
Size
Price
Status
Qty.
200μL
$600.00
In stock

0

100μL
$340.00
In stock

0

40μL
$190.00
In stock

0

Add to cart

Collected

Collect

Customized Service
Main Information
Target

CD3E

Host Species

Mouse

Reactivity

Human

Applications

IHC, WB, IF, ELISA

MW

23kD (Calculated)

23kD (Observed)

Conjugate/Modification


Unmodified

Detailed Information
Recommended Dilution Ratio
IHC 1:200-1000; WB 1:500-2000; IF 1:100-500; ELISA 1:1000-5000
Formulation
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Specificity
The antibody can specifically recognize human CD3e protein, and shows no reaction with CD3d or CD3g. In western blotting of Jurkat cell lysate, the antibody can label a 23 kDa band corresponding to CD3e.
Purification
Protein G
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
MW(Calculated)
23kD
MW(Observed)
23kD
Modification
Unmodified
Clonality
Monoclonal
Clone Number
ABT295
Isotype
IgG2a,Kappa
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human CD3, CD3E AA range: 1-100
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Specificity:
The antibody can specifically recognize human CD3e protein, and shows no reaction with CD3d or CD3g. In western blotting of Jurkat cell lysate, the antibody can label a 23 kDa band corresponding to CD3e.
show all
Gene Name:
CD3E T3E
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Protein Name:
CD3, CD3E
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Other Name:
4930549J05Rik ;
A430104F18Rik ;
AW552088 ;
Cd247 ;
CD247 antigen ;
CD247 antigen, zeta subunit ;
CD247 molecule ;
CD3 ;
CD3 antigen, delta subunit ;
CD3 delta ;
CD3 epsilon ;
CD3 eta ;
CD3 gamma ;
CD3 molecule delta polypeptide ;
CD3 molecule, epsilon polypeptide ;
CD3 molecule, gamma polypeptide ;
CD3 zeta ;
CD3-DELTA ;
CD3d ;
CD3D antigen delta polypeptide ;
CD3d antigen, delta polypeptide ;
TiT3 complex ;
CD3d molecule delta ;
CD3d molecule delta CD3 TCR complex ;
CD3d molecule, delta ;
CD3-TCR complex ;
CD3D_HUMAN ;
CD3E ;
CD3e antigen ;
CD3E antigen epsilon polypeptide ;
CD3e antigen, epsilon polypeptide ;
TiT3 complex ;
CD3e molecule epsilon ;
CD3e molecule epsilon CD3 TCR complex ;
CD3e molecule, epsilon ;
CD3-TCR complex ;
CD3epsilon ;
CD3G ;
CD3g antigen ;
CD3G antigen gamma polypeptide ;
CD3g antigen, gamma polypeptide ;
TiT3 complex ;
CD3g molecule gamma ;
CD3g molecule gamma CD3 TCR complex ;
CD3g molecule, gamma ;
CD3-TCR complex ;
CD3H ;
CD3Q ;
CD3Z ;
CD3zeta ;
Ctg3 ;
FLJ17620 ;
FLJ17664 ;
FLJ18683 ;
FLJ79544 ;
FLJ94613 ;
IMD19 ;
Leu-4 ;
MGC138597 ;
OKT3, delta chain ;
OTTHUMP00000032544 ;
T cell receptor ;
T cell receptor T3 delta chain ;
T cell receptor T3 gamma chain ;
T cell receptor T3 zeta chain ;
T cell receptor zeta chain ;
T cell surface antigen T3/Leu 4 epsilon chain ;
T cell surface glycoprotein CD3 ;
T cell surface glycoprotein CD3 delta chain ;
T cell surface glycoprotein CD3 epsilon chain ;
T cell surface glycoprotein CD3 gamma chain ;
T cell surface glycoprotein CD3 zeta chain ;
T-cell antigen receptor complex, delta subunit of T3 ;
T-cell antigen receptor complex, epsilon subunit of T3 ;
T-cell antigen receptor complex, gamma subunit of T3 ;
T-cell antigen receptor complex, zeta subunit of CD3 ;
T-cell receptor T3 delta chain ;
T-cell receptor T3 gamma chain ;
T-cell surface antigen T3/Leu-4 epsilon chain ;
T-cell surface glycoprotein CD3 delta chain ;
T-cell surface glycoprotein CD3 epsilon chain ;
T-cell surface glycoprotein CD3 gamma chain ;
T3 ;
T3d ;
T3e ;
T3g ;
T3z ;
TCRE ;
TCRk ;
Tcrz ;
TCRzeta
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Database Link:
Organism Gene ID SwissProt
Human 916; P07766;
Background:
CD3 protein contains ε、γ、δ and ζ four subunits, including extracellular, transmembrane and intracellular domains. CD3 is a T cell marker, which is not expressed by B cells. CD3 complex mediates TCR antigen recognition, leading to T cell proliferation and cytokine release. It is mainly used for the diagnosis of T-cell lymphoma, with high specificity but low sensitivity. In order to improve the accuracy of diagnosis, it is usually combined with CD45RO in clinical application.
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Function:
Function:The CD3 complex mediates signal transduction.,online information:CD3E mutation db,similarity:Contains 1 Ig-like (immunoglobulin-like) domain.,similarity:Contains 1 ITAM domain.,subunit:The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta.,
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Cellular Localization:
Membranous
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Tissue Expression:
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Research Areas:
>>Hematopoietic cell lineage ;
>>Th1 and Th2 cell differentiation ;
>>Th17 cell differentiation ;
>>T cell receptor signaling pathway ;
>>Chagas disease ;
>>Measles ;
>>Human T-cell leukemia virus 1 infection ;
>>Epstein-Barr virus infection ;
>>Human immunodeficiency virus 1 infection ;
>>PD-L1 expression and PD-1 checkpoint pathway in cancer ;
>>Primary immunodeficiency
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Catalog: YM4628
Size
Price
Status
Qty.
200μL
$600.00
In stock

0

100μL
$340.00
In stock

0

40μL
$190.00
In stock

0

Add to cart

Collected

Collect

Customized Service

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