.jpg "Ma, Zhan, Shuping Lou, and Zheng Jiang. \"PHLDA2 regulates EMT and autophagy in colorectal cancer via the PI3K/AKT signaling pathway.\" Aging (Albany NY) 12.9 (2020): 7985.")
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Main Information
Target
14-3-3 eta
Host Species
Mouse
Reactivity
Human, Mouse, Rat
Applications
WB, IHC
MW
28kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000; IHC 1:50-200
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Specificity
This antibody detects endogenous levels of 14-3-3 eta at Human, Mouse,Rat
Purification
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
28kD
Modification
Unmodified
Clonality
Monoclonal
Clone Number
5B2
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human 14-3-3 eta
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Specificity:
This antibody detects endogenous levels of 14-3-3 eta at Human, Mouse,Rat
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Gene Name:
YWHAH YWHA1
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Protein Name:
14-3-3 eta
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Other Name:
14-3-3 protein eta ;
Protein AS1 ;
Protein AS1 ;
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Database Link:
Function:
Function:Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.,similarity:Belongs to the 14-3-3 family.,subunit:Homodimer (By similarity). Interacts with many nuclear hormone receptors and cofactors including AR, ESR1, ESR2, MC2R, NR3C1, NRIP1, PPARBP and THRA. Interacts with ABL1 (phosphorylated form); the interaction retains it in the cytoplasm. Interacts with RGNEF and PCTK1 (By similarity). Weakly interacts with CDKN1B.,tissue specificity:Expressed mainly in the brain and present in other tissues albeit at lower levels.,
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Tissue Expression:
Expressed mainly in the brain and present in other tissues albeit at lower levels.
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Catalog: YM3800
Size
Price
Status
Qty.
200μL
$450.00
3 weeks
0
100μL
$280.00
3 weeks
0
40μL
$160.00
3 weeks
0
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