Catalog: YD3023
Size
Price
Status
Qty.
500μg
$1,356.00
3 weeks
0
50μg
$272.00
3 weeks
0
5μg
$52.00
3 weeks
0
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Detailed Information
Formulation
Phosphate-buffered solution
Source
Mammalian cells
Purity
>90% as determined by SDS-PAGE
Storage
-15°C to -25°C/1 year(Avoid freeze / thaw cycles)
Antigen&Target Information
Sequence:
Amino acid:35-314,with human FC tag.
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Gene Name:
CEACAM5
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Protein Name:
Carcinoembryonic antigen-related cell adhesion molecule 5 (Carcinoembryonic antigen) (CEA) (Meconium antigen 100) (CD antigen CD66e)
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Other Name:
Carcinoembryonic antigen-related cell adhesion molecule 5 ;
Carcinoembryonic antigen ;
CEA ;
Meconium antigen 100 ;
CD antigen CD66e ;
CEACAM5 ;
CEA ;
Carcinoembryonic antigen ;
CEA ;
Meconium antigen 100 ;
CD antigen CD66e ;
CEACAM5 ;
CEA ;
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Function:
Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression (PubMed:10864933, PubMed:10910050, PubMed:2803308). Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6 (PubMed:2803308). Plays a role as an oncogene by promoting tumor progression; induces resistance to anoikis of colorectal carcinoma cells (PubMed:10910050).; (Microbial infection) Receptor for E.coli Dr adhesins. Binding of E.coli Dr adhesins leads to dissociation of the homodimer.
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Cellular Localization:
Cell membrane ; Lipid-anchor, GPI-anchor . Apical cell membrane . Cell surface . Note=Localized to the apical glycocalyx surface. .
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Tissue Expression:
Expressed in columnar epithelial and goblet cells of the colon (at protein level) (PubMed:10436421). Found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon.
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Reference Citation({{totalcount}})
Catalog: YD3023
Size
Price
Status
Qty.
500μg
$1,356.00
3 weeks
0
50μg
$272.00
3 weeks
0
5μg
$52.00
3 weeks
0
Add to cart
Collected
Collect
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