Catalog: YD3014
Size
Price
Status
Qty.
500μg
$1,356.00
3 weeks
0
50μg
$272.00
3 weeks
0
5μg
$52.00
3 weeks
0
Add to cart
Collected
Collect
Detailed Information
Formulation
Phosphate-buffered solution
Source
Mammalian cells
Purity
>90% as determined by SDS-PAGE
Storage
-15°C to -25°C/1 year(Avoid freeze / thaw cycles)
Antigen&Target Information
Sequence:
Amino acid:55-229,with human FC tag.
show all
Gene Name:
CLEC1B
show all
Protein Name:
C-type lectin domain family 1 member B (C-type lectin-like receptor 2) (CLEC-2)
show all
Other Name:
C-type lectin domain family 1 member B ;
C-type lectin-like receptor 2 ;
CLEC-2 ;
CLEC1B ;
CLEC2 ;
UNQ721/PRO1384 ;
C-type lectin-like receptor 2 ;
CLEC-2 ;
CLEC1B ;
CLEC2 ;
UNQ721/PRO1384 ;
show all
Function:
C-type lectin-like receptor that functions as a platelet receptor for the lymphatic endothelial marker, PDPN (PubMed:18215137). After ligand activation, signals via sequential activation of SRC and SYK tyrosine kinases leading to activation of PLCG2 (PubMed:18955485).; (Microbial infection) Acts as a receptor for the platelet-aggregating snake venom protein rhodocytin. Rhodocytin binding leads to tyrosine phosphorylation and this promotes the binding of spleen tyrosine kinase (SYK) and initiation of downstream tyrosine phosphorylation events and activation of PLCG2 (PubMed:16174766, PubMed:18955485).; (Microbial infection) Acts as an attachment factor for Human immunodeficiency virus type 1 (HIV-1) and facilitates its capture by platelets (PubMed:16940507).
show all
Cellular Localization:
Membrane ; Single-pass type II membrane protein .
show all
Tissue Expression:
Expressed preferentially in the liver. Also expressed in immune cells of myeloid origin and on the surface of platelets.
show all
Reference Citation({{totalcount}})
Catalog: YD3014
Size
Price
Status
Qty.
500μg
$1,356.00
3 weeks
0
50μg
$272.00
3 weeks
0
5μg
$52.00
3 weeks
0
Add to cart
Collected
Collect
Recently Viewed Products
Clear allPRODUCTS
CUSTOMIZED
ABOUT US
Toggle night Mode
{{pinfoXq.title || ''}}
Catalog: {{pinfoXq.catalog || ''}}
Filter：
All
{{item.name}}
{{pinfo.title}}
-{{pinfo.catalog}}
Main Information
Target
{{pinfo.target}}
Reactivity
{{pinfo.react}}
Applications
{{pinfo.applicat}}
Conjugate/Modification
{{pinfo.coupling}}/{{pinfo.modific}}
MW (kDa)
{{pinfo.mwcalc}}
Host Species
{{pinfo.hostspec}}
Isotype
{{pinfo.isotype}}
Product {{index}}/{{pcount}}
Prev
Next
{{pvTitle}}
Scroll wheel zooms the picture
{{pvDescr}}