Catalog: KA1241C
Size
Price
Status
Qty.
96well
$470.00
2 weeks
0
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Main Information
Reactivity
Human, Mouse, Rat
Applications
ELISA
Conjugate/Modification
phosphate
Detailed Information
Storage
2-8°C/6 months,Ship by ice bag
Modification
phosphate
Detection Method
Colorimetric
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YP0296
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ELISA Kits
Total Csk Cell-Based Colorimetric ELISA Kit
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KA1241C
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Antigen&Target Information
Gene Name:
CSK
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Other Name:
Tyrosine-protein kinase CSK ;
C-Src kinase ;
Protein-tyrosine kinase CYL ;
C-Src kinase ;
Protein-tyrosine kinase CYL ;
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Database Link:
Background:
catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate. ,function:Specifically phosphorylates 'Tyr-504' on LCK , which acts as a negative regulatory site. Can also act on the LYN and FYN kinases. ,PTM:Autophosphorylation of Tyr-304 occurs only at abnormally high CSK concentrations in vitro. ,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. ,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. CSK subfamily. ,similarity:Contains 1 protein kinase domain. ,similarity:Contains 1 SH2 domain. ,similarity:Contains 1 SH3 domain. ,subcellular location:Mainly cytoplasmic , also present in lipid rafts. ,subunit:Interacts with PTPN8 (By similarity) . Interacts with phosphorylated SIT1 , PAG1 , LIME1 and TGFB1I1. ,tissue specificity:Expressed in lung and macrophages. ,
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Function:
protein amino acid phosphorylation , phosphorus metabolic process , phosphate metabolic process , intracellular signaling cascade , negative regulation of cell proliferation , phosphorylation , regulation of cell proliferation ,
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Cellular Localization:
Cytoplasm . Cell membrane . Mainly cytoplasmic , also present in lipid rafts. .
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Tissue Expression:
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Reference Citation({{totalcount}})
Catalog: KA1241C
Size
Price
Status
Qty.
96well
$470.00
2 weeks
0
Add to cart
Collected
Collect
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