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Total MAST205 Cell-Based Colorimetric ELISA Kit

-KA3794C

Catalog: KA3794C
Size
Price
Status
Qty.
96well
$330.00
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Main Information
Reactivity

Human, Mouse

Applications

ELISA

Conjugate/Modification


Unmodified

Detailed Information
Storage
2-8°C/6 months
Modification
Unmodified
Detection Method
Colorimetric
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Antigen&Target Information
Gene Name:
MAST2
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Other Name:
Microtubule-associated serine/threonine-protein kinase 2 ;
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Database Link:
Organism Gene ID SwissProt
Human 23139; Q6P0Q8;
Mouse Q60592;
Background:
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,function:Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins. Functions in a multi-protein complex in spermatid maturation. Regulates lipopolysaccharide-induced IL-12 synthesis in macrophages by forming a complex with TRAF6, resulting in the inhibition of TRAF6 NF-kappa-B activation.,PTM:Phosphorylated and ubiquitinated. N-terminal ubiquitination leads to degradation of MAST2 by proteasome-mediated proteolysis. N-terminal phosphorylation appears to be a prerequisite for ubiquitination.,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.,similarity:Contains 1 AGC-kinase C-terminal domain.,similarity:Contains 1 PDZ (DHR) domain.,similarity:Contains 1 protein kinase domain.,subcellular location:Recruited to the sub-membranous area on interaction with PC-LKC.,tissue specificity:Abundant in the testis.,
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Function:
regulation of cytokine production, reproductive developmental process, protein amino acid phosphorylation,phosphorus metabolic process, phosphate metabolic process, gamete generation, spermatogenesis, phosphorylation,sexual reproduction, multicellular organism reproduction, regulation of interleukin-12 production, regulation of cytokine biosynthetic process, regulation of interleukin-12 biosynthetic process, male gamete generation, spermatid differentiation, reproductive process in a multicellular organism, reproductive cellular process,
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Cellular Localization:
Cytoplasm, cytoskeleton . Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Recruited to the sub-membranous area on interaction with CDHR2.
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Tissue Expression:
Abundant in the testis.
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Catalog: KA3794C
Size
Price
Status
Qty.
96well
$330.00
In stock

0

Add to cart

Collected

Collect

Customized Service

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