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Total ERK 3 Cell-Based Colorimetric ELISA Kit

-KA3769C

Catalog: KA3769C
Size
Price
Status
Qty.
96well
$330.00
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Main Information
Reactivity

Human, Mouse, Rat

Applications

ELISA

Conjugate/Modification


Unmodified

Detailed Information
Storage
2-8°C/6 months
Modification
Unmodified
Detection Method
Colorimetric
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Total ERK 3 Cell-Based Colorimetric ELISA Kit
KA3769C

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Antigen&Target Information
Gene Name:
MAPK6
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Protein Name:
Mitogen-activated protein kinase 6
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Other Name:
Mitogen-activated protein kinase 6 ;
MAP kinase 6 ;
MAPK 6 ;
Extracellular signal-regulated kinase 3 ;
ERK-3 ;
MAP kinase isoform p97 ;
p97-MAPK ;
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Database Link:
Organism Gene ID SwissProt
Human 5597; Q16659;
Mouse 50772; Q61532;
Rat 58840; P27704;
Background:
The protein encoded by this gene is a member of the Ser/Thr protein kinase family, and is most closely related to mitogen-activated protein kinases (MAP kinases). MAP kinases also known as extracellular signal-regulated kinases (ERKs), are activated through protein phosphorylation cascades and act as integration points for multiple biochemical signals. This kinase is localized in the nucleus, and has been reported to be activated in fibroblasts upon treatment with serum or phorbol esters. [provided by RefSeq, Jul 2008],
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Function:
Catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,Domain:The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases.,enzyme regulation:Activated by threonine and tyrosine phosphorylation.,Function:Phosphorylates microtubule-associated protein 2 (MAP2). May promote entry in the cell cycle.,PTM:Dually phosphorylated on Thr-626 and Tyr-628, which activates the enzyme.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.,similarity:Contains 1 protein kinase domain.,tissue specificity:Highest expression in the skeletal muscle, followed by the brain. Also found in heart, placenta, lung, liver, pancreas, kidney and skin fibroblasts.,
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Cellular Localization:
Cytoplasm . Nucleus . Translocates to the cytoplasm following interaction with MAPKAPK5. .
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Tissue Expression:
Highest expression in the skeletal muscle, followed by the brain. Also found in heart, placenta, lung, liver, pancreas, kidney and skin fibroblasts.
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Catalog: KA3769C
Size
Price
Status
Qty.
96well
$330.00
In stock

0

Add to cart

Collected

Collect

Customized Service

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