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Total WTAP Cell-Based Colorimetric ELISA Kit

-KA3739C

Catalog: KA3739C
Size
Price
Status
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96well
$330.00
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Main Information
Reactivity

Human, Mouse

Applications

ELISA

Conjugate/Modification


Unmodified

Detailed Information
Storage
2-8°C/6 months
Modification
Unmodified
Detection Method
Colorimetric
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Antigen&Target Information
Gene Name:
WTAP
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Other Name:
Pre-mRNA-splicing regulator WTAP ;
Female-lethal ;
2 ;
D homolog ;
hFL ;
2 ;
D ;
WT1-associated protein ;
Wilms tumor 1-associating protein ;
show all
Database Link:
Organism Gene ID SwissProt
Human 9589; Q15007;
Mouse Q9ER69;
Background:
function:Regulates G2/M cell-cycle transition by binding to the 3' UTR of CCNA2, which enhances its stability. Impairs WT1 DNA-binding ability and inhibits expression of WT1 target genes. May be involved in mRNA splicing regulation.,induction:In smooth muscle cells, up-regulated after serum withdrawal, when cells become mature and non proliferative.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the fl(2)d family.,subunit:Interacts with WT1.,tissue specificity:Ubiquitously expressed.,
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Function:
RNA processing, mRNA processing, cell cycle, RNA splicing, mRNA metabolic process,
show all
Cellular Localization:
Nucleus speckle . Nucleus, nucleoplasm . Cytoplasm . Mainly nuclear with some fraction located in the cytoplasm. ZC3H13 is required to anchor component of the MACOM subcomplex, such as VIRMA, in the nucleus. .
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Tissue Expression:
Ubiquitously expressed.
show all
Catalog: KA3739C
Size
Price
Status
Qty.
96well
$330.00
In stock

0

Add to cart

Collected

Collect

Customized Service

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