Catalog: YP1478
Size
Price
Status
Qty.
200μL
$600.00
3 weeks
0
100μL
$340.00
3 weeks
0
50μL
$190.00
3 weeks
0
Add to cart
Collected
Collect
Main Information
Target
SATB1 Phospho Ser47
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IHC, ELISA
MW
85kD (Observed)
Conjugate/Modification
phosphate
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000; IHC 1:50-300; ELISA 1:2000-20000
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
This antibody detects endogenous levels of Human Mouse Rat SATB1 (phospho-Ser47)
Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Storage
-15°C to -25°C/1 year (Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
85kD
Modification
phosphate
Clonality
Polyclonal
Isotype
IgG
Antigen&Target Information
Immunogen:
Synthesized phosho peptide around human SATB1 (Ser47)
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Specificity:
This antibody detects endogenous levels of Human Mouse Rat SATB1 (phospho-Ser47)
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Gene Name:
SATB1
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Protein Name:
SATB1 (Ser47)
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Other Name:
DNA-binding protein SATB1 ;
Special AT-rich sequence-binding protein 1 ;
Special AT-rich sequence-binding protein 1 ;
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Background:
This gene encodes a matrix protein which binds nuclear matrix and scaffold-associating DNAs through a unique nuclear architecture. The protein recruits chromatin-remodeling factors in order to regulate chromatin structure and gene expression. [provided by RefSeq , Apr 2016] ,
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Function:
Function:Binds to DNA at special AT-rich sequences at nuclear matrix- or scaffold-associated regions. Thought to recognize the sugar-phosphate structure of double-stranded DNA. ,PTM:Sumoylated. ,similarity:Belongs to the CUT homeobox family. ,similarity:Contains 1 homeobox DNA-binding domain. ,similarity:Contains 2 CUT DNA-binding domains. ,tissue specificity:Expressed predominantly in thymus. ,
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Cellular Localization:
Nucleus matrix . Nucleus , PML body . Organized into a cage-like network anchoring loops of heterochromatin and tethering specialized DNA sequences (PubMed:12692553) . When sumoylated , localized in promyelocytic leukemia nuclear bodies (PML NBs) (PubMed:18408014) . .
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Tissue Expression:
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Reference Citation({{totalcount}})
Catalog: YP1478
Size
Price
Status
Qty.
200μL
$600.00
3 weeks
0
100μL
$340.00
3 weeks
0
50μL
$190.00
3 weeks
0
Add to cart
Collected
Collect
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