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Human FOLR1 ELISA Kit

-KE1225

Catalog: KE1225
Size
Price
Status
Qty.
5*96well
$1,850.00
3 weeks

0

2*96well
$740.00
3 weeks

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96well
$370.00
3 weeks

0

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Main Information
Reactivity

Human

Applications

ELISA

Conjugate/Modification


Unmodified

Detailed Information
Specificity
Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma
Storage
2-8°C/6 months
Modification
Unmodified
Sample Type
Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma
Detection Method
Colorimetric
Sensitivity
94-6000 pg/ml
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Antigen&Target Information
Specificity:
Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma
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Gene Name:
FOLR1
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Protein Name:
Folate receptor alpha
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Other Name:
FOLR1 ;
FOLR ;
Folate receptor alpha ;
FR-alpha ;
Adult folate-binding protein ;
FBP ;
Folate receptor 1 ;
Folate receptor ;
adult ;
KB cells FBP ;
Ovarian tumor-associated antigen MOv18
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Database Link:
Organism Gene ID SwissProt
Human 2348; P15328;
Mouse P35846;
Background:
function:Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate to the interior of cells.,PTM:Eight disulfide bonds are present.,PTM:The secreted form is derived from the membrane-bound form either by cleavage of the GPI anchor, or/and by proteolysis catalyzed by a metalloprotease.,similarity:Belongs to the folate receptor family.,tissue specificity:Exclusively expressed in tissues of epithelial origin. Expression is increased in malignant tissues. Expressed in kidney, lung and cerebellum.,
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Function:
coenzyme metabolic process, folic acid and derivative metabolic process, vitamin metabolic process, water-soluble vitamin metabolic process, amino acid transport, endocytosis, receptor-mediated endocytosis, membrane invagination,amine transport, organic acid transport, folic acid transport, membrane organization, vesicle-mediated transport,pteridine and derivative metabolic process, folic acid metabolic process, carboxylic acid transport, vitamin transport,cofactor transport, cofactor metabolic process, transmembrane transport,
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Cellular Localization:
Cell membrane ; Lipid-anchor, GPI-anchor . Apical cell membrane ; Lipid-anchor, GPI-anchor . Basolateral cell membrane ; Lipid-anchor, GPI-like-anchor . Secreted . Cytoplasmic vesicle . Cytoplasmic vesicle, clathrin-coated vesicle . Endosome . Endocytosed into cytoplasmic vesicles and then recycled to the cell membrane. .
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Tissue Expression:
Primarily expressed in tissues of epithelial origin. Expression is increased in malignant tissues. Expressed in kidney, lung and cerebellum. Detected in placenta and thymus epithelium.
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Catalog: KE1225
Size
Price
Status
Qty.
5*96well
$1,850.00
3 weeks

0

2*96well
$740.00
3 weeks

0

96well
$370.00
3 weeks

0

Add to cart

Collected

Collect

Customized Service

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