Catalog: YP1858
Size
Price
Status
Qty.
200μL
$936.00
In stock
0
100μL
$560.00
In stock
0
50μL
$300.00
In stock
0
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Collected
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Main Information
Target
Csk Phospho Tyr304
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
IHC, WB
MW
55kD (Observed)
Conjugate/Modification
Phospho
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000; IHC 1:50-200
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Specificity
This antibody detects endogenous levels of Csk (Phospho Tyr304) Rabbit pAb at Human, Mouse,Rat.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):MEyLE
Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
55kD
Modification
Phospho
Clonality
Polyclonal
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human Csk (Phospho Tyr304)
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Specificity:
This antibody detects endogenous levels of Csk (Phospho Tyr304) Rabbit pAb at Human, Mouse,Rat.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):MEyLE
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Gene Name:
CSK
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Protein Name:
Tyrosine-protein kinase CSK (C-Src kinase) (Protein-tyrosine kinase CYL)
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Other Name:
Tyrosine-protein kinase CSK ;
C-Src kinase ;
Protein-tyrosine kinase CYL ;
C-Src kinase ;
Protein-tyrosine kinase CYL ;
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Database Link:
Function:
Catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,Function:Specifically phosphorylates 'Tyr-504' on LCK, which acts as a negative regulatory site. Can also act on the LYN and FYN kinases.,PTM:Autophosphorylation of Tyr-304 occurs only at abnormally high CSK concentrations in vitro.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. CSK subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SH2 domain.,similarity:Contains 1 SH3 domain.,subcellular location:Mainly cytoplasmic, also present in lipid rafts.,subunit:Interacts with PTPN8 (By similarity). Interacts with phosphorylated SIT1, PAG1, LIME1 and TGFB1I1.,tissue specificity:Expressed in lung and macrophages.,
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Cellular Localization:
Cytoplasm . Cell membrane . Mainly cytoplasmic, also present in lipid rafts. .
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Tissue Expression:
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Research Areas:
>>Epithelial cell signaling in Helicobacter pylori infection
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Reference Citation({{totalcount}})
Catalog: YP1858
Size
Price
Status
Qty.
200μL
$936.00
In stock
0
100μL
$560.00
In stock
0
50μL
$300.00
In stock
0
Add to cart
Collected
Collect
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