function:Has heparin binding activity, and growth promoting activity. Involved in neointima formation after arterial injury, possibly by mediating leukocyte recruitment. Also involved in early fetal adrenal gland development.,induction:By heparin and retinoic acid.,similarity:Belongs to the pleiotrophin family.,subunit:Homodimer.,
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Function:
response to wounding, adrenal gland development, endocrine system development, gland development, regulation of cell division, positive regulation of cell division,
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Cellular Localization:
Secreted.
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Tissue Expression:
Expressed in various tumor cell lines. In insulinoma tissue predominantly expressed in precancerous lesions.