Synthesized phosho peptide around human HSP90α (Thr5 and 7)

This antibody detects endogenous levels of HSP 90 only when acetylated at Thr5 or Thr7,and dually phosphorylated at two sites

HSP90AA1 HSP90A HSPC1 HSPCA

HSP90α (Thr5/7)

Heat shock protein HSP 90-alpha ;
Heat shock 86 kDa ;
HSP 86 ;
HSP86 ;
Renal carcinoma antigen NY-REN-38 ;

The protein encoded by this gene is an inducible molecular chaperone that functions as a homodimer. The encoded protein aids in the proper folding of specific target proteins by use of an ATPase activity that is modulated by co-chaperones. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012],

Caution:Despite classification as a pseudogene, the existence of this protein is supported by unambiguous mass spectrometry evidence.,Function:Molecular chaperone.,Function:Molecular chaperone. Has ATPase activity.,similarity:Belongs to the heat shock protein 90 family.,subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,subunit:Homodimer. Interacts with AHSA1, SMYD3 and TOM34. Interacts with FNIP1 and HSF1.,

Nucleus . Cytoplasm . Melanosome . Cell membrane . Mitochondrion . Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

>>Protein processing in endoplasmic reticulum ;
>>PI3K-Akt signaling pathway ;
>>Necroptosis ;
>>Antigen processing and presentation ;
>>NOD-like receptor signaling pathway ;
>>IL-17 signaling pathway ;
>>Th17 cell differentiation ;
>>Progesterone-mediated oocyte maturation ;
>>Estrogen signaling pathway ;
>>Salmonella infection ;
>>Pathways in cancer ;
>>Chemical carcinogenesis - receptor activation ;
>>Prostate cancer ;
>>Lipid and atherosclerosis ;
>>Fluid shear stress and atherosclerosis