Catalog: YP0397
Size
Price
Status
Qty.
200μL
$600.00
In stock
0
100μL
$340.00
In stock
0
50μL
$190.00
In stock
0
Add to cart
Collected
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Main Information
Target
RGS16 Phospho Tyr168
Host Species
Rabbit
Reactivity
Human, Mouse, Rat, Monkey
Applications
WB, ELISA, IHC
MW
30kD (Observed)
Conjugate/Modification
Phospho
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000; IHC 1:50-300; ELISA 1:2000-20000
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
Phospho-RGS16 (Y168) Polyclonal Antibody detects endogenous levels of RGS16 protein only when phosphorylated at Y168.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):DSyPR
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
30kD
Modification
Phospho
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from human RGS16 around the phosphorylation site of Tyr168. AA range:141-190
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Specificity:
Phospho-RGS16 (Y168) Polyclonal Antibody detects endogenous levels of RGS16 protein only when phosphorylated at Y168.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):DSyPR
show all
Gene Name:
RGS16
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Protein Name:
Regulator of G-protein signaling 16
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Other Name:
RGS16 ;
RGSR ;
Regulator of G-protein signaling 16 ;
RGS16 ;
A28-RGS14P ;
Retinal-specific RGS ;
RGS-r ;
hRGS-r ;
Retinally abundant regulator of G-protein signaling
RGSR ;
Regulator of G-protein signaling 16 ;
RGS16 ;
A28-RGS14P ;
Retinal-specific RGS ;
RGS-r ;
hRGS-r ;
Retinally abundant regulator of G-protein signaling
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Background:
The protein encoded by this gene belongs to the 'regulator of G protein signaling' family. It inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits. It also may play a role in regulating the kinetics of signaling in the phototransduction cascade. [provided by RefSeq, Jul 2008],
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Function:
Function:Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha. May play a role in regulating the kinetics of signaling in the phototransduction cascade.,PTM:Palmitoylated on Cys-2 and/or Cys-12.,PTM:Phosphorylation on Tyr-168 upon EGFR stimulation. Enhanced GTPase accelerating (GAP) activity on G(i)-alpha.,similarity:Contains 1 RGS domain.,tissue specificity:Abundantly expressed in retina with lower levels of expression in most other tissues.,
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Cellular Localization:
Membrane ; Lipid-anchor .
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Tissue Expression:
Reference Citation({{totalcount}})
Catalog: YP0397
Size
Price
Status
Qty.
200μL
$600.00
In stock
0
100μL
$340.00
In stock
0
50μL
$190.00
In stock
0
Add to cart
Collected
Collect
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