TIMP-4 Polyclonal Antibody

    • 货号:YT5799
    • 应用:WB;ELISA;IHC
    • 种属:Human;Rat;Mouse;
      • 靶点:
      • TIMP-4
      • 基因名称:
      • TIMP4
      • 蛋白名称:
      • TIMP-4
      • Human Gene Id:
      • 7079
      • Human Swiss Prot No:
      • Q99727
      • Mouse Swiss Prot No:
      • Q9JHB3
      • 免疫原:
      • Synthesized peptide derived from TIMP-4 at AA range: 174-223
      • 特异性:
      • TIMP-4 Polyclonal Antibody detects endogenous levels of TIMP-4
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 其他名称:
      • Metalloproteinase inhibitor 4 (Tissue inhibitor of metalloproteinases 4) (TIMP-4)
      • 实测条带:
      • 26kD
      • 背景:
      • This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. The secreted, netrin domain-containing protein encoded by this gene is involved in regulation of platelet aggregation and recruitment and may play role in hormonal regulation and endometrial tissue remodeling. [provided by RefSeq, Jul 2008],
      • 功能:
      • function:Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them. Known to act on MMP-1, MMP-2, MMP-3, MMP-7 and MMP-9.,similarity:Belongs to the protease inhibitor I35 (TIMP) family.,similarity:Contains 1 NTR domain.,tissue specificity:Abundant in heart and present at low levels in many other tissues.,
      • 细胞定位:
      • Secreted.
      • 组织表达:
      • Abundant in heart and present at low levels in many other tissues.
      • 产品图片
      • Western Blot analysis of 3T3 cells using TIMP-4 Polyclonal Antibody diluted at 1:800. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
      • Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).