RSK3 (Phospho Thr353) rabbit pAb
- 货号：YP1635
- 应用：WB;ELISA
- 种属：Human;Mouse
- 简介：
- >>MAPK signaling pathway;>>Oocyte meiosis;>>mTOR signaling pathway;>>Thermogenesis;>>Long-term potentiation;>>Neurotrophin signaling pathway;>>Progesterone-mediated oocyte maturation;>>Insulin resistance;>>Yersinia infection;>>Chemical carcinogenesis - receptor activation
- 基因名称：
- RPS6KA2 MAPKAPK1C RSK3
- 蛋白名称：
- RSK3 (Phospho Thr353)
- 免疫原：
- Synthesized peptide derived from human RSK3 (Phospho Thr353)
- 特异性：
- This antibody detects endogenous levels of Human,Mouse RSK3 (Phospho Thr353)
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- WB 1:1000-2000 ELISA 1:5000-20000
- 纯化工艺：
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- Ribosomal protein S6 kinase alpha-2 (S6K-alpha-2;EC 2.7.11.1;90 kDa ribosomal protein S6 kinase 2;p90-RSK 2;p90RSK2;MAP kinase-activated protein kinase 1c;MAPK-activated protein kinase 1c;MAPKAP kinase 1c;MAPKAPK-1c;Ribosomal S6 kinase 3;RSK-3;pp90RSK3)
- 背景：
- catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Activated by multiple phosphorylations on threonine and serine residues.,function:Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB.,PTM:Autophosphorylated on Ser-377, as part of the activation process.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.,similarity:Contains 1 AGC-kinase C-terminal domain.,similarity:Contains 2 protein kinase domains.,subunit:Forms a complex with either ERK1 or ERK2 in quiescent cells. Transiently dissociates following mitogenic stimulation.,tissue specificity:Expressed in many tissues. Highest expression in lung and skeletal muscle.,
- 功能：
- protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, intracellular signaling cascade, protein kinase cascade, phosphorylation,
- 细胞定位：
- Nucleus . Cytoplasm .
- 组织表达：
- Widely expressed with higher expression in lung, skeletal muscle, brain, uterus, ovary, thyroid and prostate.
