IL-2 (PN0174) Nb-FC recombinant antibody
- 货号：YA0619
- 应用：ELISA
- 种属：Human
- 蛋白名称：
- Interleukin-2 (IL-2) (T-cell growth factor) (TCGF) (Aldesleukin)
- 免疫原：
- Purified recombinant Human IL-2
- 特异性：
- This recombinant monoclonal antibody can detects endogenous levels of IL-2 protein.
- 组成：
- Phosphate-buffered solution
- 来源：
- Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
- 纯化工艺：
- Recombinant Expression and Affinity purified
- 浓度：
- Please check the information on the tube
- 储存：
- -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
- 其他名称：
- IL2;Interleukin-2;IL-2;T-cell growth factor;TCGF;Aldesleukin;IL-2 nanobody;
- 背景：
- The protein encoded byThis gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor ofThis cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression ofThis gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role ofThis gene in the immune response to antigenic stimuli. [provided by RefSeq, Jul 2008]
- 功能：
- disease:A chromosomal aberration involving IL2 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with involves TNFRSF17.,Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells.,online information:Interleukin-2 entry,online information:The Singapore human mutation and polymorphism database,pharmaceutical:Available under the name Proleukin (Chiron). Used in patients with renal cell carcinoma or metastatic melanoma.,similarity:Belongs to the IL-2 family.,
- 组织表达：
- Blood,PCR rescued clones,Placenta,Spleen
