Total Melan-A Cell-Based Colorimetric ELISA Kit
- 货号:KA3317C
- 应用:ELISA
- 种属:Human
- 其他名称:
- Melanoma antigen recognized by T-cells 1 (MART-1) (Antigen LB39-AA) (Antigen SK29-AA) (Protein Melan-A)
- 背景:
- tissue specificity:Expression is restricted to melanoma and melanocyte cell lines and retina.,
- 细胞定位:
- Endoplasmic reticulum membrane; Single-pass type III membrane protein. Golgi apparatus. Golgi apparatus, trans-Golgi network membrane. Melanosome. Also found in small vesicles and tubules dispersed over the entire cytoplasm. A small fraction of the protein is inserted into the membrane in an inverted orientation. Inversion of membrane topology results in the relocalization of the protein from a predominant Golgi/post-Golgi area to the endoplasmic reticulum. Melanoma cells expressing the protein with an inverted membrane topology are more effectively recognized by specific cytolytic T-lymphocytes than those expressing the protein in its native membrane orientation.
- 组织表达:
- Expression is restricted to melanoma and melanocyte cell lines and retina.