Phospho PKD1/PKC μ (Y463) Cell-Based Colorimetric ELISA Kit

  • 货号:KA1414C
  • 应用:ELISA
  • 种属:Human;Mouse;Rat
    • 基因名称:
    • KPCD1
    • Human Gene Id:
    • 5587
    • Human Swiss Prot No:
    • Q15139
    • Mouse Swiss Prot No:
    • Q62101
    • 储存:
    • 2-8°C/6 months
    • 其他名称:
    • Serine/threonine-protein kinase D1 (EC 2.7.11.13) (Protein kinase C mu type) (Protein kinase D) (nPKC-D1) (nPKC-mu)
    • 检测方法:
    • Colorimetric
    • 背景:
    • catalytic activity:ATP + a protein = ADP + a phosphoprotein.,enzyme regulation:Activated by diacylglycerol and phorbol esters.,function:Calcium-independent, phospholipid-dependent, serine- and threonine-specific kinase involved in resistance to oxidative stress.,PTM:Phosphorylation of Ser-738 and/or Ser-742 in activated PKD is mediated by transphosphorylation (By similarity). Phosphorylation of Tyr-463 mediated by the Src/Abl pathway in response to oxidative stress activates the kinase.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.,similarity:Contains 1 PH domain.,similarity:Contains 1 protein kinase domain.,similarity:Contains 2 phorbol-ester/DAG-type zinc fingers.,subunit:Interacts (via N-terminus) with ADAP1/CENTA1. Interacts with Src.,
    • 功能:
    • protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, intracellular signaling cascade, cell proliferation, phosphorylation,
    • 细胞定位:
    • Cytoplasm . Cell membrane . Golgi apparatus, trans-Golgi network . Translocation to the cell membrane is required for kinase activation.