• 靶点：
• S100P

• 基因名称：
• S100P S100E

• 蛋白名称：
• S100P

• Human Gene Id：
• 6286

• Human Swiss Prot No：
• P25815

• 免疫原：
• Synthesized peptide derived from human S100P AA range: 1-200

• 特异性：
• The antibody can specifically recognize human S100P protein.

• 来源：
• Mouse, Monoclonal/IgG1, Kappa

• 纯化工艺：
• The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

• 储存：
• 2°C to 8°C/1 year

• 其他名称：
• Protein S100-P (Protein S100-E;S100 calcium-binding protein P)

• 背景：
• The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 4p16. This protein, in addition to binding Ca2+, also binds Zn2+ and Mg2+. This protein may play a role in the etiology of prostate cancer. [provided by RefSeq, Jul 2008],

• 功能：
• miscellaneous:This protein binds two calcium ions.,similarity:Belongs to the S-100 family.,similarity:Contains 2 EF-hand domains.,subcellular location:Colocalizes with S100PBP in the nucleus.,subunit:Homodimer. Interacts with S100PBP and S100Z.,tissue specificity:Up-regulated in various pancreatic ductal adenocarcinomas and pancreatic intraepithelial neoplasias.,

• 细胞定位：
• Nuclear, Cytoplasmic

• 组织表达：
• Detected in all of the tissues except brain, testis and small intestine, expression level is higher in placenta, heart, lung, skeletal muscle, spleen and leukocyte. Up-regulated in various pancreatic ductal adenocarcinomas and pancreatic intraepithelial neoplasias.

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