Catalog: YT7998
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
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Collected
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Main Information
Target
QIK/QSK
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB
MW
105kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
This antibody detects endogenous levels of QIK/QSK at Human, Mouse,Rat
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
105kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human QIK/QSK
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Specificity:
This antibody detects endogenous levels of QIK/QSK at Human, Mouse,Rat
show all
Gene Name:
SIK2 KIAA0781 QIK SNF1LK2
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Protein Name:
QIK/QSK
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Other Name:
Serine/threonine-protein kinase SIK2 ;
Qin-induced kinase ;
Salt-inducible kinase 2 ;
SIK-2 ;
Serine/threonine-protein kinase SNF1-like kinase 2 ;
Qin-induced kinase ;
Salt-inducible kinase 2 ;
SIK-2 ;
Serine/threonine-protein kinase SNF1-like kinase 2 ;
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Function:
Catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Activated by phosphorylation on Thr-175 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39.,Function:Phosphorylates 'Ser-794' of IRS1 in insulin-stimulated adipocytes, potentially modulating the efficiency of insulin signal transduction. Inhibits CREB activity by phosphorylating and repressing TORCs, the CREB-specific coactivators.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. AMPK subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 UBA domain.,subunit:Interacts with and phosphorylates TORC2/CRTC2.,
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Cellular Localization:
Cytoplasm . Endoplasmic reticulum membrane .
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Tissue Expression:
Brain,Colon,Lung,Testis,
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Research Areas:
>>Glucagon signaling pathway
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Signaling Pathway
Reference Citation({{totalcount}})
Catalog: YT7998
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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