Hair keratins and hair keratin-associated proteins (KAPs), such as KRTAP13-1, are the main structural proteins of hair fibers (Rogers et al., 2002 [PubMed 12359730]).[supplied by OMIM, Mar 2008],
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Function:
Caution:The sequence of 1-41 of PubMed:12359730 has not been submitted.,Function:In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.,similarity:Belongs to the PMG family.,subunit:Interacts with hair keratins.,tissue specificity:Weak expression seen in the late matrix and entire cortex area of the hair follicle.,
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Cellular Localization:
intermediate filament,
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Tissue Expression:
Weak expression seen in the late matrix and entire cortex area of the hair follicle.