This gene encodes one of testis-specific transcription factors which are essential for spermatogenesis, oogenesis and folliculogenesis. This gene is located on chromosome 13. The proteins encoded by this gene and another testis-specific transcription factor, SOHLH1, can form heterodimers, in addition to homodimers. There is a read-through locus (GeneID: 100526761) that shares sequence identity with this gene and the upstream CCDC169 (GeneID: 728591). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2013],
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Function:
Function:Probable transcription factor, which may be involved in spermatogenesis and oogenesis.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,
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Cellular Localization:
Nucleus . Cytoplasm . Translocates from the cytoplasm into the nucleus and the translocation is dependent on SOHLH1 expression. .