The protein encoded by this gene belongs to the syndecan proteoglycan family. It may play a role in the organization of cell shape by affecting the actin cytoskeleton, possibly by transferring signals from the cell surface in a sugar-dependent mechanism. Allelic variants of this gene have been associated with obesity. [provided by RefSeq, Oct 2009],
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Function:
Function:Cell surface proteoglycan that may bear heparan sulfate (By similarity). May have a role in the organization of cell shape by affecting the actin cytoskeleton, possibly by transferring signals from the cell surface in a sugar-dependent mechanism.,PTM:O-glycosylated within the Thr/Ser-rich region which could interact with lectin domains on other molecules.,similarity:Belongs to the syndecan proteoglycan family.,tissue specificity:Expressed in the nervous system, the adrenal gland, and the spleen.,
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Cellular Localization:
Cell membrane; Single-pass type I membrane protein.