Catalog: YT6566
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
Main Information
Target
GRHPR
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB
MW
36kD (Calculated)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
This antibody detects endogenous levels of GRHPR at Human/Mouse
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Calculated)
36kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
Related Products
Secondary Antibodies
Goat Anti Mouse IgG(H+L) (HRP)
RS0001
More→
Secondary Antibodies
Goat Anti Rabbit IgG(H+L) (HRP)
RS0002
More→
Primary Antibodies
β-actin (PTR2364) Mouse mAb
YM3028
More→
Primary Antibodies
GAPDH (PTR2304) Mouse mAb
YM3029
More→
Antigen&Target Information
Immunogen:
Synthesized peptide derived from human GRHPR AA range: 151-201
show all
Specificity:
This antibody detects endogenous levels of GRHPR at Human/Mouse
show all
Gene Name:
GRHPR GLXR MSTP035
show all
Protein Name:
GRHPR
show all
Background:
This gene encodes an enzyme with hydroxypyruvate reductase, glyoxylate reductase, and D-glycerate dehydrogenase enzymatic activities. The enzyme has widespread tissue expression and has a role in metabolism. Type II hyperoxaluria is caused by mutations in this gene. [provided by RefSeq, Jul 2008],
show all
Function:
Catalytic activity:Glycolate + NADP(+) = glyoxylate + NADPH.,Disease:Defects in GRHPR are the cause of hyperoxaluria primary type II (HP2) [MIM:260000]; also known as primary hyperoxaluria type II (PH2). HP2 is a disorder where the main clinical manifestation is calcium oxalate nephrolithiasis though chronic as well as terminal renal insufficiency has been described. It is characterized by an elevated urinary excretion of oxalate and L-glycerate.,Function:Enzyme with hydroxy-pyruvate reductase, glyoxylate reductase and D-glycerate dehydrogenase enzymatic activities.,similarity:Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.,subunit:Monomer.,tissue specificity:Ubiquitous. Most abundantly expressed in the liver.,
show all
Cellular Localization:
cytoplasm,peroxisomal matrix,cytosol,extracellular exosome,
show all
Tissue Expression:
Ubiquitous. Most abundantly expressed in the liver.
show all
Research Areas:
>>Glycine, serine and threonine metabolism ;
>>Pyruvate metabolism ;
>>Glyoxylate and dicarboxylate metabolism ;
>>Metabolic pathways
>>Pyruvate metabolism ;
>>Glyoxylate and dicarboxylate metabolism ;
>>Metabolic pathways
show all
Reference Citation({{totalcount}})
Catalog: YT6566
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
Recently Viewed Products
Clear allPRODUCTS
CUSTOMIZED
ABOUT US
Toggle night Mode
{{pinfoXq.title || ''}}
Catalog: {{pinfoXq.catalog || ''}}
Filter：
All
{{item.name}}
{{pinfo.title}}
-{{pinfo.catalog}}
Main Information
Target
{{pinfo.target}}
Reactivity
{{pinfo.react}}
Applications
{{pinfo.applicat}}
Conjugate/Modification
{{pinfo.coupling}}/{{pinfo.modific}}
MW (kDa)
{{pinfo.mwcalc}}
Host Species
{{pinfo.hostspec}}
Isotype
{{pinfo.isotype}}
Product {{index}}/{{pcount}}
Prev
Next
{{pvTitle}}
Scroll wheel zooms the picture
{{pvDescr}}