Catalog: YT6090
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
Main Information
Target
GCM2
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, ELISA
MW
56kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000; ELISA 1:10000-20000
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
GCM2 Polyclonal Antibody detects endogenous levels of GCM2
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
56kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human GCM2. at AA range: 21-70
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Specificity:
GCM2 Polyclonal Antibody detects endogenous levels of GCM2
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Gene Name:
GCM2
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Protein Name:
GCM2
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Other Name:
Chorion-specific transcription factor GCMb ;
hGCMb ;
GCM motif protein 2 ;
Glial cells missing homolog 2 ;
hGCMb ;
GCM motif protein 2 ;
Glial cells missing homolog 2 ;
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Background:
This gene is a homolog of the Drosophila glial cells missing gene, which is thought to act as a binary switch between neuronal and glial cell determination. The protein encoded by this gene contains a conserved N-terminal GCM motif that has DNA-binding activity. The protein is a transcription factor that acts as a master regulator of parathyroid development. It has been suggested that this transcription factor might mediate the effect of calcium on parathyroid hormone expression and secretion in parathyroid cells. Mutations in this gene are associated with hypoparathyroidism. [provided by RefSeq, Jul 2008],
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Function:
Function:Probable transcriptional regulator.,similarity:Contains 1 GCM DNA-binding domain.,
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Cellular Localization:
Nucleus .
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Tissue Expression:
Brain,Fetal brain,
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Research Areas:
>>Parathyroid hormone synthesis, secretion and action
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Reference Citation({{totalcount}})
Catalog: YT6090
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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