Catalog: YT6046
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
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Collected
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Main Information
Target
MCP-3
Host Species
Rabbit
Reactivity
Human, Rat, Mouse,
Applications
IHC, IF, ELISA
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
IHC 1:50-200; ELISA 1:10000-20000; IF 1:50-200
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
The antibody detects endogenous MCP-3
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthetic peptide from human protein at AA range: 50-99
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Specificity:
The antibody detects endogenous MCP-3
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Gene Name:
CCL7 MCP3 SCYA6 SCYA7
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Protein Name:
C-C motif chemokine 7 (Monocyte chemoattractant protein 3) (Monocyte chemotactic protein 3) (MCP-3) (NC28) (Small-inducible cytokine A7)
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Other Name:
C-C motif chemokine 7 ;
Monocyte chemoattractant protein 3 ;
Monocyte chemotactic protein 3 ;
MCP-3 ;
NC28 ;
Small-inducible cytokine A7 ;
Monocyte chemoattractant protein 3 ;
Monocyte chemotactic protein 3 ;
MCP-3 ;
NC28 ;
Small-inducible cytokine A7 ;
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Background:
This gene encodes monocyte chemotactic protein 3, a secreted chemokine which attracts macrophages during inflammation and metastasis. It is a member of the C-C subfamily of chemokines which are characterized by having two adjacent cysteine residues. The protein is an in vivo substrate of matrix metalloproteinase 2, an enzyme which degrades components of the extracellular matrix. This gene is part of a cluster of C-C chemokine family members on chromosome 17q. [provided by RefSeq, Jul 2008],
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Function:
Function:Chemotactic factor that attracts monocytes and eosinophils, but not neutrophils. Augments monocyte anti-tumor activity. Also induces the release of gelatinase B. This protein can bind heparin. Binds to CCR1, CCR2 and CCR3.,online information:CCL7 entry,PTM:O-glycosylated.,similarity:Belongs to the intercrine beta (chemokine CC) family.,subunit:Monomer.,
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Cellular Localization:
Secreted.
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Tissue Expression:
Blood,Colon,Osteosarcoma,
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Research Areas:
>>Cytokine-cytokine receptor interaction ;
>>Viral protein interaction with cytokine and cytokine receptor ;
>>Chemokine signaling pathway ;
>>IL-17 signaling pathway
>>Viral protein interaction with cytokine and cytokine receptor ;
>>Chemokine signaling pathway ;
>>IL-17 signaling pathway
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Signaling Pathway
Organismal Systems >> Immune system >> IL-17 signaling pathway
Organismal Systems >> Immune system >> Chemokine signaling pathway
Environmental Information Processing >> Signaling molecules and interaction >> Cytokine-cytokine receptor interaction
Environmental Information Processing >> Signaling molecules and interaction >> Viral protein interaction with cytokine and cytokine receptor
Reference Citation({{totalcount}})
Catalog: YT6046
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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