Catalog: YT5987
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
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Collected
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Main Information
Target
Abin-2
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
IHC, IF, ELISA
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
IHC 1:50-200; ELISA 1:10000-20000; IF 1:50-200
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
The antibody detects endogenous Abin-2
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthetic peptide from human protein at AA range: 61-110
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Specificity:
The antibody detects endogenous Abin-2
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Gene Name:
TNIP2 ABIN2 FLIP1
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Protein Name:
TNFAIP3-interacting protein 2 (A20-binding inhibitor of NF-kappa-B activation 2) (ABIN-2) (Fetal liver LKB1-interacting protein)
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Other Name:
TNFAIP3-interacting protein 2 ;
A20-binding inhibitor of NF-kappa-B activation 2 ;
ABIN-2 ;
Fetal liver LKB1-interacting protein ;
A20-binding inhibitor of NF-kappa-B activation 2 ;
ABIN-2 ;
Fetal liver LKB1-interacting protein ;
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Background:
This gene encodes a protein which acts as an inhibitor of NFkappaB activation. The encoded protein is also involved in MAP/ERK signaling pathway in specific cell types. It may be involved in apoptosis of endothelial cells. Alternative splicing results in multiple transcript variants. A pseudogene related to this gene is located on the X chromosome.[provided by RefSeq, May 2014],
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Function:
Function:Inhibits NF-kappa-B activation by blocking the interaction of RIPK1 with its downstream effector IKBKG. Forms a ternary complex with NFKB1 and MAP3K8 but appears to function upstream of MAP3K8 in the TLR4 signaling pathway that regulates MAP3K8 activation.,subunit:Interacts with STK11, TNFAIP3, IKBKG, NFKB1, MAP3K8 and RIPK1.,tissue specificity:Ubiquitously expressed in all tissues examined.,
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Cellular Localization:
Cytoplasm . Nucleus .
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Tissue Expression:
Ubiquitously expressed in all tissues examined.
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Reference Citation({{totalcount}})
Catalog: YT5987
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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