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Catalog: YT5475
Size
Price
Status
Qty.
200μL
$450.00
In stock

0

100μL
$280.00
In stock

0

40μL
$150.00
In stock

0

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Main Information
Target

CD300f

Host Species

Rabbit

Reactivity

Human, Rat, Mouse,

Applications

WB, IHC, IF, ELISA

MW

32kD (Observed)

Conjugate/Modification


Unmodified

Detailed Information
Recommended Dilution Ratio
WB 1:500-1:2000; IHC: 1:100-1:300; ELISA 1:20000; IF 1:50-200
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
CD300f Polyclonal Antibody detects endogenous levels of CD300f protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
32kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from the Internal region of human CD300LF. AA range:41-90
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Specificity:
CD300f Polyclonal Antibody detects endogenous levels of CD300f protein.
show all
Gene Name:
CD300LF
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Protein Name:
CMRF35-like molecule 1
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Other Name:
CD300LF ;
CD300F ;
CLM1 ;
IGSF13 ;
IREM1 ;
NKIR ;
CMRF35-like molecule 1 ;
CLM-1 ;
CD300 antigen-like family member F ;
Immune receptor expressed on myeloid cells 1 ;
IREM-1 ;
Immunoglobulin superfamily member 13 ;
IgSF13 ;
NK inhibitory receptor ;
CD300f
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Database Link:
Organism Gene ID SwissProt
Human 146722; Q8TDQ1;
Mouse 246746; Q6SJQ7;
Rat 287818; Q566E6;
Background:
This gene encodes a member of the CD300 protein family. Members of this family are cell surface glycoproteins with a single IgV-like extracellular domain, and are involved in the regulation of immune response. The encoded protein is an inhibitory receptor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014],
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Function:
Function:Acts as an inhibitory receptor for myeloid cells and mast cells. Inhibits osteoclast formation.,PTM:Phosphorylated on tyrosine.,similarity:Belongs to the CD300 family.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subunit:Interacts with PTPN6/SHP-1 in a tyrosine phosphorylation dependent manner.,tissue specificity:Highly expressed in spleen, peripheral blood leukocte and monocyte, and lung. Weakly expressed in thymus, heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, testis, ovary, small intestine or colon. Expressed selectively in monocytes and monocyte-related cells.,
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Cellular Localization:
Cell membrane ; Single-pass type I membrane protein .
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Tissue Expression:
Highly expressed in spleen, peripheral blood leukocyte and monocyte, and lung. Weakly expressed in thymus, heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, testis, ovary, small intestine or colon. Expressed selectively in monocytes and monocyte-related cells.
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Catalog: YT5475
Size
Price
Status
Qty.
200μL
$450.00
In stock

0

100μL
$280.00
In stock

0

40μL
$150.00
In stock

0

Add to cart

Collected

Collect

Customized Service

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