Catalog: YT5405
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
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Main Information
Target
CD294
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB, IHC, IF, ELISA
MW
43kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-1:2000; IHC: 1:100-1:300; ELISA 1:20000; IF 1:50-200
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
CD294 Polyclonal Antibody detects endogenous levels of CD294 protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
43kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from the Internal region of human PTGDR2. AA range:161-210
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Specificity:
CD294 Polyclonal Antibody detects endogenous levels of CD294 protein.
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Gene Name:
PTGDR2
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Protein Name:
Prostaglandin D2 receptor 2
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Other Name:
PTGDR2 ;
CRTH2 ;
DL1R ;
GPR44 ;
Prostaglandin D2 receptor 2 ;
Chemoattractant receptor-homologous molecule expressed on Th2 cells ;
G-protein coupled receptor 44 ;
CD294
CRTH2 ;
DL1R ;
GPR44 ;
Prostaglandin D2 receptor 2 ;
Chemoattractant receptor-homologous molecule expressed on Th2 cells ;
G-protein coupled receptor 44 ;
CD294
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Database Link:
Background:
This gene encodes a G-protein-coupled receptor that is preferentially expressed in CD4+ effector T helper 2 (Th2) cells. This protein is a prostaglandin D2 receptor that mediates the pro-inflammatory chemotaxis of eosinophils, basophils, and Th2 lymphocytes generated during allergic inflammation. Single nucleotide polymorphisms in the 3' UTR of this gene have been associated with asthma susceptibility.[provided by RefSeq, Mar 2011],
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Function:
Function:Orphan receptor.,similarity:Belongs to the G-protein coupled receptor 1 family.,
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Cellular Localization:
Cell membrane ; Multi-pass membrane protein . Internalized receptors colocalized with RAB11A. .
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Tissue Expression:
Widespread expression. High expression in stomach, small intestine, heart and thymus. Intermediate expression in colon, spinal cord and peripheral blood and low expression in brain, skeletal muscle and spleen. Expressed also on Th2- and Tc2- type cells, eosinophils and basophils.
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Reference Citation({{totalcount}})
Catalog: YT5405
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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