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β-1,4-Gal-T5 Rabbit pAb

-YT5010

Catalog: YT5010
Size
Price
Status
Qty.
200μL
$450.00
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100μL
$280.00
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40μL
$150.00
In stock

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Main Information
Target

B4GALT5

Host Species

Rabbit

Reactivity

Human, Mouse

Applications

WB, ELISA

MW

40kD (Observed)

Conjugate/Modification


Unmodified

Detailed Information
Recommended Dilution Ratio
WB 1:500-1:2000; ELISA 1:10000; Not yet tested in other applications.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
β-1,4-Gal-T5 Polyclonal Antibody detects endogenous levels of β-1,4-Gal-T5 protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
40kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from human B4GALT5. AA range:321-370
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Specificity:
β-1,4-Gal-T5 Polyclonal Antibody detects endogenous levels of β-1,4-Gal-T5 protein.
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Gene Name:
B4GALT5
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Protein Name:
Beta-1,4-galactosyltransferase 5
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Other Name:
B4GALT5 ;
Beta-1 ;
4-galactosyltransferase 5 ;
Beta-1,4-GalTase 5 ;
Beta4Gal-T5 ;
b4Gal-T5 ;
Beta-1,4-GalT II ;
UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 5 ;
UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 5
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Database Link:
Organism Gene ID SwissProt
Human 9334; O43286;
Mouse 56336; Q9JMK0;
Background:
This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The function of the enzyme encoded by this gene is not clear. This gene was previously designated as B4GALT4 but was renamed
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Function:
cofactor:Manganese.,Function:Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.,online information:Beta-1,4-galactosyltransferase 5,online information:GlycoGene database,pathway:Protein modification; protein glycosylation.,similarity:Belongs to the glycosyltransferase 7 family.,subcellular location:Trans cisternae of Golgi stack.,tissue specificity:Ubiquitously expressed.,
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Cellular Localization:
Golgi apparatus, Golgi stack membrane ; Single-pass type II membrane protein. Golgi apparatus . Trans cisternae of Golgi stack. .
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Tissue Expression:
Ubiquitously expressed.
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Research Areas:
>>Mucin type O-glycan biosynthesis ;
>>Sphingolipid metabolism ;
>>Metabolic pathways
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Catalog: YT5010
Size
Price
Status
Qty.
200μL
$450.00
In stock

0

100μL
$280.00
In stock

0

40μL
$150.00
In stock

0

Add to cart

Collected

Collect

Customized Service

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