Catalog: YT4952
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
Main Information
Target
ZIS
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IHC, IF, ELISA
MW
34kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:10000; Not yet tested in other applications.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
ZIS Polyclonal Antibody detects endogenous levels of ZIS protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
34kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from human ZNF265. AA range:106-155
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Specificity:
ZIS Polyclonal Antibody detects endogenous levels of ZIS protein.
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Gene Name:
ZRANB2
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Protein Name:
Zinc finger Ran-binding domain-containing protein 2
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Other Name:
ZRANB2 ;
ZIS ;
ZNF265 ;
Zinc finger Ran-binding domain-containing protein 2 ;
Zinc finger protein 265 ;
Zinc finger ;
splicing
ZIS ;
ZNF265 ;
Zinc finger Ran-binding domain-containing protein 2 ;
Zinc finger protein 265 ;
Zinc finger ;
splicing
show all
Database Link:
Background:
domain:The RanBP2-type zinc fingers mediate binding to RNA.,function:Splice factor required for alternative splicing of TRA2B/SFRS10 transcripts. May interfere with constitutive 5'-splice site selection.,PTM:Isoform 2 is phosphorylated on Ser-310 upon DNA damage, probably by ATM or ATR.,sequence caution:Intron retention.,similarity:Belongs to the ZRANB2 family.,similarity:Contains 2 RanBP2-type zinc fingers.,subunit:Interacts with the C-terminal half of SNRNP70, the Arg/Ser-rich domain of XE7 as well as with U2AF1 and CLK1.,
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Function:
Domain:The RanBP2-type zinc fingers mediate binding to RNA.,Function:Splice factor required for alternative splicing of TRA2B/SFRS10 transcripts. May interfere with constitutive 5'-splice site selection.,PTM:Isoform 2 is phosphorylated on Ser-310 upon DNA damage, probably by ATM or ATR.,sequence Caution:Intron retention.,similarity:Belongs to the ZRANB2 family.,similarity:Contains 2 RanBP2-type zinc fingers.,subunit:Interacts with the C-terminal half of SNRNP70, the Arg/Ser-rich domain of XE7 as well as with U2AF1 and CLK1.,
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Cellular Localization:
Nucleus .
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Tissue Expression:
Brain,Epithelium,Fetal brain,Fetal kidney,Liver,Skin,Testis,Uterus,
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Reference Citation({{totalcount}})
Catalog: YT4952
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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