Catalog: YT4927
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
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Main Information
Target
ZAC1
Host Species
Rabbit
Reactivity
Human
Applications
WB, ELISA
MW
50kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-1:2000; ELISA 1:10000; Not yet tested in other applications.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
ZAC1 Polyclonal Antibody detects endogenous levels of ZAC1 protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
50kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from human PLAGL1. AA range:311-360
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Specificity:
ZAC1 Polyclonal Antibody detects endogenous levels of ZAC1 protein.
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Gene Name:
PLAGL1
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Protein Name:
Zinc finger protein PLAGL1
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Other Name:
PLAGL1 ;
LOT1 ;
ZAC ;
Zinc finger protein PLAGL1 ;
Lost on transformation 1 ;
LOT-1 ;
Pleiomorphic adenoma-like protein 1 ;
Tumor supressor ZAC
LOT1 ;
ZAC ;
Zinc finger protein PLAGL1 ;
Lost on transformation 1 ;
LOT-1 ;
Pleiomorphic adenoma-like protein 1 ;
Tumor supressor ZAC
show all
Background:
This gene encodes a C2H2 zinc finger protein that functions as a suppressor of cell growth. This gene is often deleted or methylated and silenced in cancer cells. In addition, overexpression of this gene during fetal development is thought to be the causal factor for transient neonatal diabetes mellitus (TNDM). Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding two different protein isoforms. The P1 downstream promoter of this gene is imprinted, with preferential expression from the paternal allele in many tissues. [provided by RefSeq, Nov 2015],
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Function:
Function:Shows weak transcriptional activatory activity. Transcriptional regulator of the type 1 receptor for pituitary adenylate cyclase-activating polypeptide.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 7 C2H2-type zinc fingers.,
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Cellular Localization:
Nucleus .
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Tissue Expression:
Reference Citation({{totalcount}})
Catalog: YT4927
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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