Catalog: YT4750
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
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Collected
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Main Information
Target
TRP2
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB, IHC, IF, ELISA
MW
60kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-1:2000; IF 1:200-1:1000; ELISA 1:40000; Not yet tested in other applications.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
TRP2 Polyclonal Antibody detects endogenous levels of TRP2 protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
60kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from human DCT. AA range:51-100
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Specificity:
TRP2 Polyclonal Antibody detects endogenous levels of TRP2 protein.
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Gene Name:
DCT
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Protein Name:
L-dopachrome tautomerase
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Other Name:
DCT ;
TYRP2 ;
L-dopachrome tautomerase ;
DCT ;
DT ;
L-dopachrome Delta-isomerase ;
Tyrosinase-related protein 2 ;
TRP-2 ;
TRP2
TYRP2 ;
L-dopachrome tautomerase ;
DCT ;
DT ;
L-dopachrome Delta-isomerase ;
Tyrosinase-related protein 2 ;
TRP-2 ;
TRP2
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Background:
catalytic activity:L-dopachrome = 5,6-dihydroxyindole-2-carboxylate.,cofactor:Binds 2 zinc ions per subunit.,function:Involved in regulating eumelanin and phaeomelanin levels.,pathway:Pigment biosynthesis; melanin biosynthesis.,similarity:Belongs to the tyrosinase family.,subunit:Tyrosinase, TYRP1 and TYRP2 may form a multienzyme complex.,
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Function:
Catalytic activity:L-dopachrome = 5,6-dihydroxyindole-2-carboxylate.,cofactor:Binds 2 zinc ions per subunit.,Function:Involved in regulating eumelanin and phaeomelanin levels.,pathway:Pigment biosynthesis; melanin biosynthesis.,similarity:Belongs to the tyrosinase family.,subunit:Tyrosinase, TYRP1 and TYRP2 may form a multienzyme complex.,
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Cellular Localization:
Melanosome membrane ; Single-pass type I membrane protein . Melanosome . Proper trafficking to melanosome is regulated by SGSM2, ANKRD27, RAB9A, RAB32 and RAB38. .
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Tissue Expression:
Liver,Lymphnode melanoma metastases,Mammary gland,Melanoma,
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Research Areas:
>>Tyrosine metabolism ;
>>Metabolic pathways ;
>>Melanogenesis
>>Metabolic pathways ;
>>Melanogenesis
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Reference Citation({{totalcount}})
Catalog: YT4750
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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