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TCP-1 α Rabbit pAb

-YT4583

Catalog: YT4583
Size
Price
Status
Qty.
200μL
$450.00
In stock

0

100μL
$280.00
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40μL
$150.00
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Main Information
Target

TCP-1 α

Host Species

Rabbit

Reactivity

Human, Mouse, Rat

Applications

WB, ELISA

MW

60kD (Observed)

Conjugate/Modification


Unmodified

Detailed Information
Recommended Dilution Ratio
WB 1:500-1:2000; ELISA 1:10000; Not yet tested in other applications.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
TCP-1 α Polyclonal Antibody detects endogenous levels of TCP-1 α protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
60kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from the Internal region of human TCP-1 α.
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Specificity:
TCP-1 α Polyclonal Antibody detects endogenous levels of TCP-1 α protein.
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Gene Name:
TCP1
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Protein Name:
T-complex protein 1 subunit alpha
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Other Name:
TCP1 ;
CCT1 ;
CCTA ;
T-complex protein 1 subunit alpha ;
TCP-1-alpha ;
CCT-alpha
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Database Link:
Organism Gene ID SwissProt
Human 6950; P17987;
Mouse 21454; P11983;
Rat 24818; P28480;
Background:
The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized. In addition, three pseudogenes that appear to be derived from this gene have been found. [provided by RefSeq, Jun 2010],
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Function:
Function:Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.,similarity:Belongs to the TCP-1 chaperonin family.,subunit:Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter. Interacts with PACRG.,
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Cellular Localization:
Cytoplasm, cytosol . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome .
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Catalog: YT4583
Size
Price
Status
Qty.
200μL
$450.00
In stock

0

100μL
$280.00
In stock

0

40μL
$150.00
In stock

0

Add to cart

Collected

Collect

Customized Service

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