Catalog: YT4418
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
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Main Information
Target
SRp40
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
IHC, IF, ELISA
MW
31kD (Calculated)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000; Not yet tested in other applications.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
SRp40 Polyclonal Antibody detects endogenous levels of SRp40 protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Calculated)
31kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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SRp40 Rabbit pAb
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Secondary Antibodies
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RS0001
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Secondary Antibodies
Goat Anti Rabbit IgG(H+L) (HRP)
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from human SFRS5. AA range:71-120
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Specificity:
SRp40 Polyclonal Antibody detects endogenous levels of SRp40 protein.
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Gene Name:
SRSF5
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Protein Name:
Serine/arginine-rich splicing factor 5
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Other Name:
SRSF5 ;
HRS ;
SFRS5 ;
SRP40 ;
Serine/arginine-rich splicing factor 5 ;
Delayed-early protein HRS ;
Pre-mRNA-splicing factor SRP40 ;
Splicing factor ;
arginine/serine-rich 5
HRS ;
SFRS5 ;
SRP40 ;
Serine/arginine-rich splicing factor 5 ;
Delayed-early protein HRS ;
Pre-mRNA-splicing factor SRP40 ;
Splicing factor ;
arginine/serine-rich 5
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Database Link:
Background:
The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016],
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Function:
Function:Plays a role in constitutive splicing and can modulate the selection of alternative splice sites.,PTM:Extensively phosphorylated on serine residues in the RS domain.,similarity:Belongs to the splicing factor SR family.,similarity:Contains 2 RRM (RNA recognition motif) domains.,subunit:Found in a pre-mRNA splicing complex with SFRS4, SFRS5, SNRNP70, SNRPA1, SRRM1 and SRRM2.,
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Cellular Localization:
Nucleus.
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Tissue Expression:
Research Areas:
>>Spliceosome ;
>>Herpes simplex virus 1 infection
>>Herpes simplex virus 1 infection
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Reference Citation({{totalcount}})
Catalog: YT4418
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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