Catalog: YT3992
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
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Main Information
Target
Rag C
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, ELISA, IHC, CoIP
MW
44kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000; IHC 1:50-300; IP 1:50-200; ELISA 1:2000-20000
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
Rag C Polyclonal Antibody detects endogenous levels of Rag C protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
44kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from human RRAGC. AA range:302-351
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Specificity:
Rag C Polyclonal Antibody detects endogenous levels of Rag C protein.
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Gene Name:
RRAGC
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Protein Name:
Ras-related GTP-binding protein C
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Other Name:
RRAGC ;
Ras-related GTP-binding protein C ;
Rag C ;
RagC ;
GTPase-interacting protein 2 ;
TIB929
Ras-related GTP-binding protein C ;
Rag C ;
RagC ;
GTPase-interacting protein 2 ;
TIB929
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Background:
This gene encodes a member of the GTR/RAG GTP-binding protein family. The encoded protein is a monomeric guanine nucleotide-binding protein which forms a heterodimer with RRAGA and RRAGB and is primarily localized to the cytoplasm. The encoded protein promotes intracellular localization of the mTOR complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012],
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Function:
Function:Has guanine nucleotide-binding activity but weak intrinsic GTPase activity.,similarity:Belongs to the GTR/RAG GTP-binding protein family.,subcellular location:Predominantly cytoplasmic. May shuttle between the cytoplasm and nucleus, depending on the bound nucleotide state of associated RRAGA.,subunit:Forms a heterodimer with RRAGA in a sequence-independent manner. Binds GTP. Interacts with NOL8 and RRAGB.,
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Cellular Localization:
Cytoplasm . Nucleus . Lysosome . Predominantly cytoplasmic. May shuttle between the cytoplasm and nucleus, depending on the bound nucleotide state of associated RRAGA (PubMed:11073942). .
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Tissue Expression:
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Research Areas:
>>Autophagy - animal ;
>>mTOR signaling pathway ;
>>Shigellosis
>>mTOR signaling pathway ;
>>Shigellosis
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Signaling Pathway
Reference Citation({{totalcount}})
Catalog: YT3992
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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