Catalog: YT3091
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
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Collected
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Main Information
Target
NF-YB
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IHC, IF, ELISA
MW
29kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
NF-YB Polyclonal Antibody detects endogenous levels of NF-YB protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
29kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from human NFYB. AA range:1-50
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Specificity:
NF-YB Polyclonal Antibody detects endogenous levels of NF-YB protein.
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Gene Name:
NFYB
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Protein Name:
Nuclear transcription factor Y subunit beta
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Other Name:
NFYB ;
HAP3 ;
Nuclear transcription factor Y subunit beta ;
CAAT box DNA-binding protein subunit B ;
Nuclear transcription factor Y subunit B ;
NF-YB
HAP3 ;
Nuclear transcription factor Y subunit beta ;
CAAT box DNA-binding protein subunit B ;
Nuclear transcription factor Y subunit B ;
NF-YB
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Database Link:
Background:
The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. This gene product, subunit B, forms a tight dimer with the C subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Observation of the histone nature of these subunits is supported by two types of evidence; protein sequence alignments and experiments with mutants. [provided by RefSeq, Jul 2008],
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Function:
Domain:Can be divided into 3 domains: the weakly conserved A domain, the highly conserved B domain thought to be involved in subunit interaction and DNA binding, and the Glu-rich C domain.,Function:Stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters, for example in type 1 collagen, albumin and beta-actin genes.,similarity:Belongs to the NFYB/HAP3 subunit family.,subunit:Heterotrimeric transcription factor composed of three components, NF-YA, NF-YB and NF-YC. NF-YB and NF-YC must interact and dimerize for NF-YA association and DNA binding.,
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Cellular Localization:
Nucleus.
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Tissue Expression:
Urinary bladder,
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Research Areas:
>>Antigen processing and presentation ;
>>Tuberculosis ;
>>Human T-cell leukemia virus 1 infection
>>Tuberculosis ;
>>Human T-cell leukemia virus 1 infection
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Reference Citation({{totalcount}})
Catalog: YT3091
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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