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Neurexin IIIβ Rabbit pAb

-YT3057

Catalog: YT3057
Size
Price
Status
Qty.
200μL
$450.00
In stock

0

100μL
$280.00
In stock

0

40μL
$150.00
In stock

0

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Main Information
Target

Neurexin IIIβ

Host Species

Rabbit

Reactivity

Human, Rat, Mouse,

Applications

WB, ELISA, IHC

MW

70kD (Observed)

Conjugate/Modification


Unmodified

Detailed Information
Recommended Dilution Ratio
WB 1:500-2000; IHC 1:50-300; ELISA 1:2000-20000
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
Neurexin IIIβ Polyclonal Antibody detects endogenous levels of Neurexin IIIβ protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
70kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from Neurexin IIIβ . at AA range: 30-110
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Specificity:
Neurexin IIIβ Polyclonal Antibody detects endogenous levels of Neurexin IIIβ protein.
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Gene Name:
NRXN3
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Protein Name:
Neurexin-3-beta
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Other Name:
NRXN3 ;
KIAA0743 ;
Neurexin-3-beta ;
Neurexin III-beta
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Database Link:
Organism Gene ID SwissProt
Human 9369; Q9HDB5;
Mouse Q8C985;
Background:
NRXN3 (neurexin 3) encodes a member of a family of proteins that function in the nervous system as receptors and cell adhesion molecules. Extensive alternative splicing and the use of alternative promoters results in multiple transcript variants and protein isoforms for this gene, but the full-length nature of many of these variants has not been determined. Transcripts that initiate from an upstream promoter encode alpha isoforms, which contain epidermal growth factor-like (EGF-like) sequences and laminin G domains. Transcripts initiating from the downstream promoter encode beta isoforms, which lack EGF-like sequences. Genetic variation at this locus has been associated with a range of behavioral phenotypes, including alcohol dependence and autism spectrum disorder.
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Function:
cell morphogenesis, cell morphogenesis involved in differentiation, regulation of neurotransmitter levels, generation of a signal involved in cell-cell signaling, neurotransmitter transport, cell motion, cell adhesion, cell-cell signaling, synaptic transmission, neurotransmitter secretion, axonogenesis, axon guidance, synaptogenesis, transmission of nerve impulse, biological adhesion, cell projection organization, neuron differentiation, neuron projection development,secretion by cell, cellular component morphogenesis, cell part morphogenesis, extracellular structure organization,secretion, neuron development, cell morphogenesis involved in neuron differentiation, neuron projection morphogenesis, cell projection morphogenesis, synapse organization, neurological system process,
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Cellular Localization:
Membrane ; Single-pass type I membrane protein .
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Tissue Expression:
Expressed in the blood vessel walls (at protein level).
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Catalog: YT3057
Size
Price
Status
Qty.
200μL
$450.00
In stock

0

100μL
$280.00
In stock

0

40μL
$150.00
In stock

0

Add to cart

Collected

Collect

Customized Service

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