Catalog: YT2988
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
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0
40μL
$150.00
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Main Information
Target
N-cadherin
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IHC, IF, ELISA
MW
100-140kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:10000; Not yet tested in other applications.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
N-cadherin Polyclonal Antibody detects endogenous levels of N-cadherin protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
100-140kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from human CDH2. AA range:721-770
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Specificity:
N-cadherin Polyclonal Antibody detects endogenous levels of N-cadherin protein.
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Gene Name:
CDH2
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Protein Name:
Cadherin-2
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Other Name:
CDH2 ;
CDHN ;
NCAD ;
Cadherin-2 ;
CDw325 ;
Neural cadherin ;
N-cadherin ;
CD antigen CD325
CDHN ;
NCAD ;
Cadherin-2 ;
CDw325 ;
Neural cadherin ;
N-cadherin ;
CD antigen CD325
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Database Link:
Background:
This gene encodes a classical cadherin and member of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein is proteolytically processed to generate a calcium-dependent cell adhesion molecule and glycoprotein. This protein plays a role in the establishment of left-right asymmetry, development of the nervous system and the formation of cartilage and bone. [provided by RefSeq, Nov 2015],
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Function:
Function:Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH2 may be involved in neuronal recognition mechanism.,similarity:Contains 5 cadherin domains.,subunit:Interacts with CDCP1.,
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Cellular Localization:
Cell membrane ; Single-pass type I membrane protein . Cell membrane, sarcolemma . Cell junction . Cell surface . Colocalizes with TMEM65 at the intercalated disk in cardiomyocytes. Colocalizes with OBSCN at the intercalated disk and at sarcolemma in cardiomyocytes. .
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Tissue Expression:
Brain,Epithelium,Liver,
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Research Areas:
>>Cell adhesion molecules ;
>>Arrhythmogenic right ventricular cardiomyopathy
>>Arrhythmogenic right ventricular cardiomyopathy
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Signaling Pathway
Reference Citation({{totalcount}})
Catalog: YT2988
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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