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Catalog: YT2701
Size
Price
Status
Qty.
200μL
$450.00
In stock

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100μL
$280.00
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40μL
$150.00
In stock

0

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Main Information
Target

MEF-2

Host Species

Rabbit

Reactivity

Human, Mouse

Applications

WB, IHC, IF, ELISA

MW

38kD (Observed)

Conjugate/Modification


Unmodified

Detailed Information
Recommended Dilution Ratio
WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
MEF-2B Polyclonal Antibody detects endogenous levels of MEF-2B protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
38kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from human MEF2B. AA range:51-100
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Specificity:
MEF-2B Polyclonal Antibody detects endogenous levels of MEF-2B protein.
show all
Gene Name:
MEF2B
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Protein Name:
Myocyte-specific enhancer factor 2B
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Other Name:
MEF2B ;
XMEF2 ;
Myocyte-specific enhancer factor 2B ;
RSRFR2 ;
Serum response factor-like protein 2
show all
Database Link:
Organism Gene ID SwissProt
Human 4207; Q02080;
Mouse O55087;
Background:
This gene represents numerous read-through transcripts that span GeneID:729991 and 100271849. Many read-through transcripts are predicted to be nonsense-mediated decay (NMD) candidates, and are thought to be non-coding. Some transcripts are predicted to be capable of translation reinitiation at a downstream AUG, resulting in expression of at least one isoform of myocyte enhancer factor 2B (MEF2B) from this read-through locus. At least one additional MEF2B variant and isoform can be expressed from a downstream promoter, and is annotated on GeneID:100271849. [provided by RefSeq, Oct 2010],
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Function:
Function:Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific genes. Activates transcription via this element. May be involved in muscle-specific and/or growth factor-related transcription.,similarity:Belongs to the MEF2 family.,similarity:Contains 1 MADS-box domain.,similarity:Contains 1 Mef2-type DNA-binding domain.,subunit:Interacts with HDAC7 (By similarity). Heterodimer. Interacts with HDAC9.,tissue specificity:Expressed in skeletal and cardiac muscle and brain.,
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Cellular Localization:
Nucleus.
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Tissue Expression:
Expressed in skeletal and cardiac muscle and brain.
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Research Areas:
>>cGMP-PKG signaling pathway ;
>>Apelin signaling pathway
show all
Catalog: YT2701
Size
Price
Status
Qty.
200μL
$450.00
In stock

0

100μL
$280.00
In stock

0

40μL
$150.00
In stock

0

Add to cart

Collected

Collect

Customized Service

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