Catalog: YT2581
Size
Price
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Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
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Main Information
Target
LPAAT-γ
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, ELISA, IHC
MW
40kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000; IHC 1:50-300; ELISA 1:2000-20000
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
LPAAT-γ Polyclonal Antibody detects endogenous levels of LPAAT-γ protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
40kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from human AGPAT3. AA range:121-170
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Specificity:
LPAAT-γ Polyclonal Antibody detects endogenous levels of LPAAT-γ protein.
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Gene Name:
AGPAT3
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Protein Name:
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma
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Other Name:
AGPAT3 ;
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma ;
1-acylglycerol-3-phosphate O-acyltransferase 3 ;
1-AGP acyltransferase 3 ;
1-AGPAT 3 ;
Lysophosphatidic acid acyltransferase gamma ;
LPAAT-gamma
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma ;
1-acylglycerol-3-phosphate O-acyltransferase 3 ;
1-AGP acyltransferase 3 ;
1-AGPAT 3 ;
Lysophosphatidic acid acyltransferase gamma ;
LPAAT-gamma
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Background:
The protein encoded by this gene is an acyltransferase that converts lysophosphatidic acid into phosphatidic acid, which is the second step in the de novo phospholipid biosynthetic pathway. The encoded protein may be an integral membrane protein. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008],
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Function:
Catalytic activity:Acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate.,Domain:The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.,Function:Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.,pathway:Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 2/3.,similarity:Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.,
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Cellular Localization:
Endoplasmic reticulum membrane ; Multi-pass membrane protein . Nucleus envelope .
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Tissue Expression:
Widely expressed with highest levels in testis, pancreas and kidney, followed by spleen, lung, adipose tissue and liver.
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Research Areas:
>>Glycerolipid metabolism ;
>>Glycerophospholipid metabolism ;
>>Metabolic pathways ;
>>Phospholipase D signaling pathway
>>Glycerophospholipid metabolism ;
>>Metabolic pathways ;
>>Phospholipase D signaling pathway
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Signaling Pathway
Reference Citation({{totalcount}})
Catalog: YT2581
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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