Catalog: YT2464
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
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Main Information
Target
KEPI
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IHC, IF, ELISA
MW
20kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000; Not yet tested in other applications.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
KEPI Polyclonal Antibody detects endogenous levels of KEPI protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
20kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from human PPP1R14C. AA range:51-100
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Specificity:
KEPI Polyclonal Antibody detects endogenous levels of KEPI protein.
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Gene Name:
PPP1R14C
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Protein Name:
Protein phosphatase 1 regulatory subunit 14C
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Other Name:
PPP1R14C ;
KEPI ;
Protein phosphatase 1 regulatory subunit 14C ;
Kinase-enhanced PP1 inhibitor ;
PKC-potentiated PP1 inhibitory protein ;
Serologically defined breast cancer antigen NY-BR-81
KEPI ;
Protein phosphatase 1 regulatory subunit 14C ;
Kinase-enhanced PP1 inhibitor ;
PKC-potentiated PP1 inhibitory protein ;
Serologically defined breast cancer antigen NY-BR-81
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Database Link:
Background:
The degree of protein phosphorylation is regulated by a balance of protein kinase and phosphatase activities. Protein phosphatase-1 (PP1; see MIM 176875) is a signal-transducing phosphatase that influences neuronal activity, protein synthesis, metabolism, muscle contraction, and cell division. PPP1R14C is an inhibitor of PP1 (Liu et al., 2002 [PubMed 11812771]).[supplied by OMIM, Feb 2010],
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Function:
Function:Inhibitor of PPP1CA. Has over 600-fold higher inhibitory activity when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction.,similarity:Belongs to the PP1 inhibitor family.,tissue specificity:Detected in breast cancer.,
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Cellular Localization:
Cytoplasm . Membrane ; Peripheral membrane protein .
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Tissue Expression:
Detected in breast cancer.
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Reference Citation({{totalcount}})
Catalog: YT2464
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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