Catalog: YT2185
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
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Main Information
Target
HMG-17
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
IHC, IF, ELISA
MW
10kD (Calculated)
15-17kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:40000; Not yet tested in other applications.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
HMG-17 Polyclonal Antibody detects endogenous levels of HMG-17 protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Calculated)
10kD
MW(Observed)
15-17kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from human HMG17. AA range:1-50
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Specificity:
HMG-17 Polyclonal Antibody detects endogenous levels of HMG-17 protein.
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Gene Name:
HMGN2
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Protein Name:
Non-histone chromosomal protein HMG-17
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Other Name:
HMGN2 ;
HMG17 ;
Non-histone chromosomal protein HMG-17 ;
High mobility group nucleosome-binding domain-containing protein 2
HMG17 ;
Non-histone chromosomal protein HMG-17 ;
High mobility group nucleosome-binding domain-containing protein 2
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Background:
high mobility group nucleosomal binding domain 2(HMGN2) Homo sapiens The protein encoded by this gene binds nucleosomal DNA and is associated with transcriptionally active chromatin. Along with a similar protein, HMGN1, the encoded protein may help maintain an open chromatin configuration around transcribable genes. The protein has also been found to have antimicrobial activity against bacteria, viruses and fungi. [provided by RefSeq, Oct 2014],
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Function:
Function:Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in an unique chromatin conformation.,mass spectrometry: PubMed:10739259,PTM:Phosphorylation favors cytoplasmic localization.,similarity:Belongs to the HMGN family.,subcellular location:Cytoplasmic enrichment upon phosphorylation.,
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Cellular Localization:
Nucleus . Cytoplasm . Cytoplasmic enrichment upon phosphorylation.
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Tissue Expression:
Reference Citation({{totalcount}})
Catalog: YT2185
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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