Catalog: YT1467
Size
Price
Status
Qty.
200μL
$450.00
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100μL
$280.00
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40μL
$150.00
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Main Information
Target

EDG-5

Host Species

Rabbit

Reactivity

Human, Mouse, Rat

Applications

WB, IHC, IF, ELISA

MW

39kD (Observed)

Conjugate/Modification


Unmodified

Detailed Information
Recommended Dilution Ratio
WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:10000; Not yet tested in other applications.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
EDG-5 Polyclonal Antibody detects endogenous levels of EDG-5 protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
39kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from human EDG5. AA range:261-310
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Specificity:
EDG-5 Polyclonal Antibody detects endogenous levels of EDG-5 protein.
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Gene Name:
S1PR2
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Protein Name:
Sphingosine 1-phosphate receptor 2
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Other Name:
S1PR2 ;
EDG5 ;
Sphingosine 1-phosphate receptor 2 ;
S1P receptor 2 ;
S1P2 ;
Endothelial differentiation G-protein coupled receptor 5 ;
Sphingosine 1-phosphate receptor Edg-5 ;
S1P receptor Edg-5
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Database Link:
Organism Gene ID SwissProt
Human 9294; O95136;
Mouse 14739; P52592;
Rat 29415; P47752;
Background:
This gene encodes a member of the G protein-coupled receptors, as well as the EDG family of proteins. The encoded protein is a receptor for sphingosine 1-phosphate, which participates in cell proliferation, survival, and transcriptional activation. Defects in this gene have been associated with congenital profound deafness. [provided by RefSeq, Mar 2016],
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Function:
Function:Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis.,similarity:Belongs to the G-protein coupled receptor 1 family.,
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Cellular Localization:
Cell membrane; Multi-pass membrane protein.
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Tissue Expression:
show all
Research Areas:
>>Sphingolipid signaling pathway ;
>>Neuroactive ligand-receptor interaction
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Catalog: YT1467
Size
Price
Status
Qty.
200μL
$450.00
In stock

0

100μL
$280.00
In stock

0

40μL
$150.00
In stock

0

Add to cart

Collected

Collect

Customized Service

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